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Stomach

Amylase + lipase + protease + cellulase + hyoscyamine

Digestive enzymes
Other names: Kutrase

FAA guidance

Acceptable with conditions.

Wait

no wait (the FAA's MedGuide)

Other FAA documents add more.

Source: FAA, MedGuide (FAA Office of Aerospace Medicine medication reference). FAA date 1 October 2026. Checked by Crosscheck 14 October 2026

The FAA's MedGuide lists amylase + lipase + protease + cellulase + hyoscyamine (Kutrase) as allowed, for supplement, with no wait after the first dose, after later doses or after the final dose, used per label directions.

Track your medications
Compare FAA documents: amylase + lipase + protease + cellulase + hyoscyamineWhat each of the two FAA documents says, in plain wordsOpen

Wait

  • for hyoscyamine taken for colitis, the FAA's colitis worksheet says no flying for 48 hours after use

The MedGuide defines allowed as acceptable for use while performing flight or safety-related duties, provided the condition is stable/aeromedically acceptable and no adverse side effects are present, and says wait times are not determined solely by the medication: an extended observation period may be required to verify clinical stability of the condition.

The FAA's CACI – Colitis Worksheet, for hyoscyamine taken for Crohn's disease, ulcerative colitis, microscopic colitis or irritable bowel syndrome, says use 1 to 2 times a week with no side effects and no flying for 48 hours after use; that rule is on the hyoscyamine entry.

Show the FAA's words: amylase + lipase + protease + cellulase + hyoscyamineThe official FAA wording: four passages, each with its document and dateOpen
FAA, MedGuide (FAA Office of Aerospace Medicine medication reference) · FAA date 1 October 2026
Generic: amylase + lipase + protease + cellulase + hyoscyamine
Brand Name: Kutrase
Drug Class: Digestive enzymes
Underlying Condition: Supplement
Use: ALLOW
INITIAL Wait Time (after first dose): None
SUBSEQUENT Dose Wait Time (after each dose): None
DISCONTINUATION Wait Time (after final dose): None
Frequency Use Limit: Per label directions
FAA, CACI – Colitis Worksheet · FAA date 29 April 2026
Cause of Colitis
Crohn’s disease, ulcerative colitis, microscopic colitis, or irritable bowel syndrome
Medications for condition
One or more of the following:
hyoscyamine - use 1-2 times a week with no side effects and no-fly 48 hours after use
FAA, MedGuide (FAA Office of Aerospace Medicine medication reference) · FAA date 1 October 2026
ALLOWED: The medication is acceptable for use while performing flight or safety-related duties, provided the condition is stable/aeromedically acceptable and no adverse side effects are present.
FAA, MedGuide (FAA Office of Aerospace Medicine medication reference) · FAA date 1 October 2026
Underlying Condition: Evaluating medication use requires considering the impact of safety of flight from both the medication and underlying condition. Wait times are not determined solely by the medication; an extended observation period may be required to verify clinical stability of the condition.
Sources and dates: amylase + lipase + protease + cellulase + hyoscyamineTwo FAA documents, with the FAA's date and when Crosscheck checked themOpen

See also

Medication guidance alone does not determine whether a pilot is medically qualified to fly. The underlying condition, dosage, side effects, medication combinations, and certification history may affect FAA eligibility.

For informational purposes only. Not legal or medical advice.