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Alpha-2 agonist eye drops

Alpha-2 agonist eye drop for glaucoma
Other names: brimonidine, Alphagan P, apraclonidine, Iopidine

FAA guidance

Acceptable in the FAA document cited.

Examiner

CACI: the examiner can issue when the condition's worksheet criteria are met. Applicants for first- or second-class must provide the worksheet's information annually; applicants for third-class with each required exam

Source: FAA, Glaucoma and Ocular Hypertension Medications. FAA date 27 August 2025. Checked by Crosscheck 14 October 2026

The FAA's glaucoma medication sheet lists apraclonidine (Iopidine) and brimonidine (Alphagan P) as CACI glaucoma medication, as a single agent or in a combination product.

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Compare FAA documents: Alpha-2 agonist eye dropsWhat each of the two FAA documents says, in plain wordsOpen

The FAA's CACI – Glaucoma Worksheet lists alpha agonist (Alphagan) among its acceptable medications.

The FAA's CACI – Glaucoma Worksheet says the examiner can issue if the pilot meets all of its acceptable certification criteria, which include the examiner's review of a current, detailed clinical progress note from a clinic visit with the treating physician or specialist no more than 90 days before the exam.

Show the FAA's words: Alpha-2 agonist eye dropsThe official FAA wording: two passages, each with its document and dateOpen
FAA, Glaucoma and Ocular Hypertension Medications · FAA date 27 August 2025
CACI Glaucoma Medications (as a single agent or in a combination product)
Alpha2 Agonist: apraclonidine (Iopidine), brimonidine (Alphagan P)
FAA, CACI – Glaucoma Worksheet · FAA date 13 April 2022
To determine the applicant’s eligibility for certification, the AME must review a current, detailed Clinical Progress Note generated from a clinic visit with the treating physician or specialist no more than 90 days prior to the AME exam
If the applicant meets ALL the acceptable certification criteria listed below, the AME can issue
Medications [ ] None or Prostaglandin analogs (Xalatan, Lumigan, Travatan or Travatan Z), Carbonic anhydrase inhibitor (Trusopt and Azopt), Beta blockers (Timoptic, etc), or Alpha agonist (Alphagan). Combination eye drops are acceptable
Sources and dates: Alpha-2 agonist eye dropsTwo FAA documents, with the FAA's date and when Crosscheck checked themOpen

See also

Medication guidance alone does not determine whether a pilot is medically qualified to fly. The underlying condition, dosage, side effects, medication combinations, and certification history may affect FAA eligibility.

For informational purposes only. Not legal or medical advice.