Cholesterol
Inclisiran
Antilipemic Small Interfering Ribonucleic Acid (siRNA) Agent
Other names: Leqvio
Wait
24 hours
after the first dose
Different waits apply in other cases.
The FAA's MedGuide lists inclisiran (Leqvio) as allowed, for hypercholesterolemia, with a wait of 24 hours after the first dose and 4 hours after each dose and the same after the final dose, used as prescribed.
Track your medicationsMore detail: inclisiranThe rest of Crosscheck's reading, in plain wordsOpen
Wait
- 4 hours after each dose
- 4 hours after the final dose
The MedGuide defines allowed as acceptable for use while performing flight or safety-related duties, provided the condition is stable/aeromedically acceptable and no adverse side effects are present, and says wait times are not determined solely by the medication: an extended observation period may be required to verify clinical stability of the condition.
- 24 hours after the first dose: ground observation
- 4 hours after each dose: ground observation
- 4 hours after stopping: ground observation
Show the FAA's words: inclisiranThe official FAA wording: three passages, each with its document and dateOpen
Generic: inclisiran
Brand Name: Leqvio
Drug Class: Antilipemic Small Interfering Ribonucleic Acid (siRNA) Agent
Underlying Condition: Hypercholesterolemia
Use: ALLOW
INITIAL Wait Time (after first dose): 24 hours
SUBSEQUENT Dose Wait Time (after each dose): 4 hours
DISCONTINUATION Wait Time (after final dose): Same as subsequent dose wait time
Frequency Use Limit: As prescribed
ALLOWED: The medication is acceptable for use while performing flight or safety-related duties, provided the condition is stable/aeromedically acceptable and no adverse side effects are present.
Underlying Condition: Evaluating medication use requires considering the impact of safety of flight from both the medication and underlying condition. Wait times are not determined solely by the medication; an extended observation period may be required to verify clinical stability of the condition.