Crosscheck

Your medical. Crosschecked.

Sleep

Melatonin

Supplement

FAA guidance

Generally acceptable.

FAA label

GENERALLY SAFE TO FLY

Source: FAA, What Over-the-Counter (OTC) Medications Can I Take and Still Be Safe to Fly?. FAA date 28 August 2024. Checked by Crosscheck 14 October 2026

The FAA's over-the-counter guide lists melatonin in its "Generally Safe to Fly" column for sleep aid products, with a note that taking it at the wrong time can worsen jet lag and cause daytime drowsiness.

Track your medications
More detail: melatoninThe rest of Crosscheck's reading, in plain wordsOpen

The same guide says never to fly after taking a new medication for the first time until at least 48 hours have passed and no side effects are noted.

FAA rule for sleep medication: The FAA puts all currently available sleep aids on its Do Not Fly list, prescription and over-the-counter alike, and if the pilot uses one routinely, the FAA's table says the examiner should defer. Its sleep aids page says occasional or limited use of sleep aids, such as for circadian rhythm disruption in commercial air operations, is allowable for pilots, and daily or nightly use of sleep aids is not allowed regardless of the underlying cause or reason. It also says medical conditions that chronically interfere with sleep are disqualifying regardless of whether a sleep aid is used or not. FAA, DO NOT ISSUE – DO NOT FLY Medications and general No Fly wait times

Show the FAA's words: melatoninThe official FAA wording: two passages, each with its document and dateOpen
FAA, What Over-the-Counter (OTC) Medications Can I Take and Still Be Safe to Fly? · FAA date 28 August 2024
Sleep aid
GENERALLY SAFE TO FLY
GO
melatonin (not an antihistamine)
NOTE: Taking melatonin at the wrong time can actually worsen jetlag and cause daytime drowsiness.
FAA, What Over-the-Counter (OTC) Medications Can I Take and Still Be Safe to Fly? · FAA date 28 August 2024
NEVER FLY AFTER TAKING A NEW MEDICATION FOR THE FIRST TIME UNTIL AT LEAST 48 HOURS HAVE PASSED AND NO SIDE EFFECTS ARE NOTED.
Sources and dates: melatoninOne FAA document, with the FAA's date and when Crosscheck checked itOpen

See also

Medication guidance alone does not determine whether a pilot is medically qualified to fly. The underlying condition, dosage, side effects, medication combinations, and certification history may affect FAA eligibility.

For informational purposes only. Not legal or medical advice.