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Cholesterol

Other cholesterol medications

Bile acid sequestrant, omega-3 ester, ACL inhibitor, niacin
Other names: niacin, Niaspan, Niacor, cholestyramine, Questran, Prevalite

FAA guidance

Acceptable with conditions.

Wait

24 hours

after the first dose (the FAA's MedGuide, whose table has no entry for colesevelam)

Two FAA documents give different waits. Both are below.

Examiner

The examiner can issue when the document's criteria are met

FAA label

ACCEPTABLE

Source: FAA, Cholesterol Medication. FAA date 27 August 2025. Checked by Crosscheck 14 October 2026

The FAA's two documents on these cholesterol medicines give different waits.

Track your medications
Compare FAA documents: Other cholesterol medicationsWhat each of the two FAA documents says, in plain wordsOpen

The FAA's documents differ. The FAA's cholesterol sheet gives every cholesterol medicine a 48-hour ground trial when starting; the FAA's MedGuide, newer and written medicine by medicine, gives this one 24 hours after the first dose. Both are current FAA documents and both name the medicine, so neither is set aside.

Wait

  • 48-hour ground trial when starting (the FAA's cholesterol sheet)

The FAA's MedGuide names niacin (Niacor, Niaspan), cholestyramine (Prevalite, Questran), colestipol (Colestid), omega-3-acid ethyl esters (Lovaza), icosapent ethyl (Vascepa) and bempedoic acid (Nexletol) as allowed, with a wait of 24 hours after the first dose and none after later doses or after the final dose, used as prescribed; its table has no entry for colesevelam (Welchol).

The FAA's cholesterol sheet lists bile acid sequestrants, omega-3 esters, bempedoic acid and niacin as acceptable cholesterol medication and says all drug classes require the minimum standard 48-hour initial ground trial. The MedGuide defines allowed as acceptable for use while performing flight or safety-related duties, provided the condition is stable/aeromedically acceptable and no adverse side effects are present.

  • 24 hours after the first dose: ground observation
  • 48 hours after starting: ground observation
Show the FAA's words: Other cholesterol medicationsThe official FAA wording: two passages, each with its document and dateOpen
FAA, Cholesterol Medication · FAA date 27 August 2025
All drug classes require the minimum standard 48-hour initial ground trial. ACCEPTABLE Cholesterol Medications (as a single agent or in any combination product)
Bile Acid Sequestrant: cholestyramine (Prevalite; Questran), colesevelam (Welchol), colestipol (Colestid). Omega-3-acid ethyl esters: omega-3-acid ethyl esters (Lovaza), icosapent ethyl (Vascepa). Adenosine Triphosphate-Citrate Lyase (ACL) Inhibitor: bempedoic acid (Nexletol). Nicotinic acid: niacin (Niaspan).
Generic: niacin
Brand Name: Niacor; Niaspan [INTL]
Drug Class: Antilipemic Agent, Vitamin
Underlying Condition: Hypercholesterolemia; Hyperlipidemia; Supplement
Use: ALLOW
INITIAL Wait Time (after first dose): 24 hours
SUBSEQUENT Dose Wait Time (after each dose): None
DISCONTINUATION Wait Time (after final dose): None
Frequency Use Limit: As prescribed
Generic: cholestyramine
Brand Name: Prevalite; Questran
Drug Class: Bile Acid Sequestrant
Underlying Condition: Hypercholesterolemia; Hyperlipidemia
Use: ALLOW
INITIAL Wait Time (after first dose): 24 hours
SUBSEQUENT Dose Wait Time (after each dose): None
DISCONTINUATION Wait Time (after final dose): None
Frequency Use Limit: As prescribed
Generic: colestipol
Brand Name: Colestid
Drug Class: Bile Acid Sequestrant
Underlying Condition: Hypercholesterolemia; Hyperlipidemia; Irritable bowel syndrome (IBS) [OL]
Use: ALLOW
INITIAL Wait Time (after first dose): 24 hours
SUBSEQUENT Dose Wait Time (after each dose): None
DISCONTINUATION Wait Time (after final dose): None
Frequency Use Limit: As prescribed
Generic: omega-3-acid ethyl esters
Brand Name: Lovaza; Omacor [INTL]
Drug Class: Omega-3 Fatty Acids
Underlying Condition: Hyperlipidemia; Hypertriglyceridemia
Use: ALLOW
INITIAL Wait Time (after first dose): 24 hours
SUBSEQUENT Dose Wait Time (after each dose): None
DISCONTINUATION Wait Time (after final dose): None
Frequency Use Limit: As prescribed
Generic: icosapent ethyl (E-EPA)
Brand Name: Vascepa
Drug Class: Omega-3 Fatty Acids
Underlying Condition: Hypercholesterolemia; Hyperlipidemia
Use: ALLOW
INITIAL Wait Time (after first dose): 24 hours
SUBSEQUENT Dose Wait Time (after each dose): None
DISCONTINUATION Wait Time (after final dose): None
Frequency Use Limit: As prescribed
Generic: bempedoic acid
Brand Name: Nexletol; Nilemdo [INTL]
Drug Class: Adenosine Triphosphate-Citrate Lyase (ACL) Inhibitor
Underlying Condition: Hypercholesterolemia
Use: ALLOW
INITIAL Wait Time (after first dose): 24 hours
SUBSEQUENT Dose Wait Time (after each dose): None
DISCONTINUATION Wait Time (after final dose): None
Frequency Use Limit: As prescribed
FAA, MedGuide (FAA Office of Aerospace Medicine medication reference) · FAA date 1 October 2026
ALLOWED: The medication is acceptable for use while performing flight or safety-related duties, provided the condition is stable/aeromedically acceptable and no adverse side effects are present.
Sources and dates: Other cholesterol medicationsTwo FAA documents, with the FAA's date and when Crosscheck checked themOpen

See also

Medication guidance alone does not determine whether a pilot is medically qualified to fly. The underlying condition, dosage, side effects, medication combinations, and certification history may affect FAA eligibility.

For informational purposes only. Not legal or medical advice.