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Oral overactive bladder medication: oxybutynin, tolterodine, solifenacin

Oral anticholinergic
Other names: oxybutynin, Ditropan, tolterodine, Detrol, solifenacin, Vesicare

FAA guidance

Do not issue.

Examiner

Do not issue: the examiner cannot issue a certificate

FAA label

DO NOT ISSUE

Source: FAA, DO NOT ISSUE – DO NOT FLY Medications and general No Fly wait times. FAA date 30 September 2026. Checked by Crosscheck 14 October 2026

The FAA's Do Not Issue list, under oral anticholinergics, names over-active bladder medications with tertiary structure that carry strong warnings about the potential for sedation and impaired cognition — tolterodine, oxybutynin and solifenacin — and the FAA's table says the examiner should defer the exam; it also says do not issue a medical certificate.

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More detail: Oral overactive bladder medication: oxybutynin, tolterodine, solifenacinThe rest of Crosscheck's reading, in plain wordsOpen

The oxybutynin skin patch (Oxytrol for women) has its own entry.

Show the FAA's words: Oral overactive bladder medication: oxybutynin, tolterodine, solifenacinThe official FAA wording: one passage, each with its document and dateOpen
FAA, DO NOT ISSUE – DO NOT FLY Medications and general No Fly wait times · FAA date 30 September 2026
DO NOT ISSUE (DNI) MEDICATIONS
If the applicant is taking any of the following medications, AMEs should DEFER the exam. DO NOT issue a medical certificate to applicants who are using any of the following drug classes or medications for any condition:
ANTICHOLINERGICS (ORAL)
atropine
Over-active bladder (OAB) medications with tertiary structure that carry strong warnings about the potential for sedation and impaired cognition:
tolterodine (Detrol)
oxybutynin (Ditropan)
solifenacin (Vesicare)
Sources and dates: Oral overactive bladder medication: oxybutynin, tolterodine, solifenacinOne FAA document, with the FAA's date and when Crosscheck checked itOpen

See also

Medication guidance alone does not determine whether a pilot is medically qualified to fly. The underlying condition, dosage, side effects, medication combinations, and certification history may affect FAA eligibility.

For informational purposes only. Not legal or medical advice.