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Cholesterol

PCSK9 inhibitors

Monoclonal antibody, PCSK9 inhibitor
Other names: alirocumab, Praluent, evolocumab, Repatha

FAA guidance

Acceptable with conditions.

Wait

48 hours

ground trial when starting

Examiner

The examiner can issue when the document's criteria are met

FAA label

ACCEPTABLE

Source: FAA, Cholesterol Medication. FAA date 27 August 2025. Checked by Crosscheck 14 October 2026

The FAA lists PCSK9 inhibitors as acceptable cholesterol medication, with the minimum standard 48-hour ground trial when starting.

Track your medications
More detail: PCSK9 inhibitorsThe FAA rules behind this answerOpen
  • 48 hours after starting: ground observation
Show the FAA's words: PCSK9 inhibitorsThe official FAA wording: one passage, each with its document and dateOpen
FAA, Cholesterol Medication · FAA date 27 August 2025
All drug classes require the minimum standard 48-hour initial ground trial. ACCEPTABLE Cholesterol Medications (as a single agent or in any combination product)
Monoclonal Antibody - PCSK9 Inhibitor: alirocumab (Praluent), evolocumab (Repatha).
Sources and dates: PCSK9 inhibitorsOne FAA document, with the FAA's date and when Crosscheck checked itOpen

See also

Medication guidance alone does not determine whether a pilot is medically qualified to fly. The underlying condition, dosage, side effects, medication combinations, and certification history may affect FAA eligibility.

For informational purposes only. Not legal or medical advice.