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Weight loss

Two diabetes medications for weight loss or prediabetes

Combination of two diabetic medication components
Other names: metformin + GLP-1, metformin with Wegovy

FAA guidance

Special issuance required.

Source: FAA, Weight Loss Medications. FAA date 26 August 2026. Checked by Crosscheck 14 October 2026

The FAA lists a combination of two diabetes medication components for weight loss as conditionally acceptable, requiring a special issuance.

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Compare FAA documents: Two diabetes medications for weight loss or prediabetesWhat each of the three FAA documents says, in plain wordsOpen

The FAA's weight loss management and prediabetes tables both say that for treatment with two or more diabetic medication (non-insulin) components, the examiner should defer and submit the information to the FAA for a possible special issuance; if the medication is taken for weight loss and the person has a diagnosis of diabetes, they point to the FAA's diabetes guidance.

Show the FAA's words: Two diabetes medications for weight loss or prediabetesThe official FAA wording: three passages, each with its document and dateOpen
FAA, Weight Loss Medications · FAA date 26 August 2026
CONDITIONALLY ACCEPTABLE Weight Loss Medications (Requires SI). Combination of two diabetic medications (2 components) e.g., metformin + GLP-1 agonist. See Acceptable Combinations of Diabetes Medications
FAA, Weight Loss Management Disposition Table · FAA date 27 March 2024
C.
Treated with
TWO (2) or more
diabetic medication
(non-insulin) components
Note: If the medication is taken for weight loss, and the individual has a diagnosis of diabetes, see www.faa.gov/go/diabetic
DEFER
Submit the information to the FAA for a possible Special Issuance
FAA, Prediabetes Disposition Table · FAA date 27 September 2023
C.
Treated with
TWO (2) or more
diabetic medication
(non-insulin) components
Note: If the medication is taken for weight loss, and the individual has a diagnosis of diabetes, see www.faa.gov/go/diabetic
DEFER
Submit the information to the FAA for a possible Special Issuance
Sources and dates: Two diabetes medications for weight loss or prediabetesThree FAA documents, with the FAA's date and when Crosscheck checked themOpen

See also

Medication guidance alone does not determine whether a pilot is medically qualified to fly. The underlying condition, dosage, side effects, medication combinations, and certification history may affect FAA eligibility.

For informational purposes only. Not legal or medical advice.