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Prediabetes

What the FAA's documents say about prediabetes, in plain words, with the FAA's own words one press away.

FAA term: Prediabetes (Metabolic Syndrome, Impaired Fasting Glucose, Insulin Resistance, or Glucose Elevation/Intolerance)

FAA source: CACI – Prediabetes Worksheet. FAA date 26 August 2026. Checked by Crosscheck 14 October 2026

Short version

The FAA's table sorts it into three rows.

How the FAA's table sorts Prediabetes
SituationWhat the examiner doesPathway
Row ALifestyle changes
Examiner issues
Examiner can issue
Row BOne diabetes medicine, not insulin
Worksheet
CACI
Row CTwo or more diabetes medicines, not insulin
Defers to the FAA
Special Issuance
Show the FAA's words: the FAA's table for Prediabetes
  1. Row A · Examiner can issue

    Treated with lifestyle intervention. The table says ISSUE where the examiner can determine the condition is under control, the current medications are acceptable and there are no symptoms that would interfere with flight duties, and has the examiner annotate this information in Block 60.

    Treated with lifestyle intervention If the AME can determine the condition is: Under control; Current medications are acceptable; and The individual has no symptoms that would interfere with flight duties: ISSUE Annotate this information in Block 60.

    FAA source: Prediabetes Disposition Table. FAA date 27 September 2023. Checked by Crosscheck 14 October 2026

  2. Row B · CACI

    Treated with one non-insulin diabetic medication component. The table sends the examiner to the CACI worksheet for prediabetes and the Weight Loss Management or Prediabetes Status Report, and says this requires a current, detailed progress note from the treating physician and an A1C performed no more than 90 days before the exam. If the pilot meets all the worksheet's criteria and is otherwise qualified, the table says ISSUE, and has the examiner annotate the correct CACI statement in Block 60 and keep the required supporting information on file.

    Treated with ONE diabetic medication (non-insulin) component See the CACI – Prediabetes Worksheet and the Weight Loss Management or Prediabetes Status Report … This requires a current, detailed Clinical Progress Note from the treating physician and Hemoglobin A1c lab performed no more than 90 days before the AME exam. … If the pilot meets all CACI worksheet criteria and is otherwise qualified: ISSUE Annotate the correct CACI statement in Block 60 and keep the required supporting information on file.

    FAA source: Prediabetes Disposition Table. FAA date 27 September 2023. Checked by Crosscheck 14 October 2026

  3. Row C · Special Issuance

    Treated with two or more non-insulin diabetic medication components. The table has the examiner defer and submit either the Diabetes or Hyperglycemia on Medications Status Report or a current, detailed progress note from the treating physician containing all the required information listed in that status report, to the FAA for a possible Special Issuance, and annotate the elements or findings in Block 60.

    Treated with TWO (2) or more diabetic medication (non-insulin) components … Submit either: … Diabetes or Hyperglycemia on Medications Status Report … A current, detailed Clinical Progress Note from the treating physician which contains all the required information listed in the above status report. … DEFER Submit the information to the FAA for a possible Special Issuance Annotate (elements or findings) in Block 60.

    FAA source: Prediabetes Disposition Table. FAA date 27 September 2023. Checked by Crosscheck 14 October 2026

  4. A note on the table, 1

    In its row for two or more components, the table notes that where the medication is taken for weight loss and the individual has a diagnosis of diabetes, the reader should see the address it prints.

    Treated with TWO (2) or more diabetic medication (non-insulin) components … Note: If the medication is taken for weight loss, and the individual has a diagnosis of diabetes, see www.faa.gov/go/diabetic

    FAA source: Prediabetes Disposition Table. FAA date 27 September 2023. Checked by Crosscheck 14 October 2026

  5. A note on the table, 2

    The table points polycystic ovarian syndrome to its own page.

    Note: For Polycystic Ovarian Syndrome (PCOS), see that page.

    FAA source: Prediabetes Disposition Table. FAA date 27 September 2023. Checked by Crosscheck 14 October 2026

What the pathway names mean

The FAA pathways for prediabetes

Which exam

Which one describes yours?

The FAA's table sorts it these ways. Choose yours to see its plan.

Your step-by-step plan

  1. Step 1: Before you begin

    Whether you have ever had an A1C of 6.5% or greater, and what your medication is used for.

    This worksheet is for prediabetes, in a pilot who has never had an A1C of 6.5% or greater.

    It is not for

    • Not: Anyone who has ever had an A1C of 6.5% or greater
    • Not: Diabetes in remission (diet-controlled)
    • Not: Diabetes treated with medication, including insulin
    • Not: Diabetes insipidus
    Show the FAA's words: Before you begin

    If the applicant has EVER had an A1C OF 6.5% OR GREATER, DO NOT USE THIS CACI.

    FAA source: CACI – Prediabetes Worksheet. FAA date 26 August 2026; checked by Crosscheck 14 October 2026.

    AME MUST REVIEW ACCEPTABLE CERTIFICATION CRITERIA

    Medication is used for:

    Note: Diabetes in remission (diet-controlled), diabetes treated with medication (including insulin), or diabetes insipidus DO NOT qualify for this CACI.

    [ ] Prediabetes

    FAA source: CACI – Prediabetes Worksheet. FAA date 26 August 2026; checked by Crosscheck 14 October 2026.

  2. Step 2: Progress note, A1C and status report form

    The records the examiner reviews, and what your treating doctor finds.Three things to bring
    • Progress note

      Within 90 days before the exam

      A current, detailed progress note from a clinic visit with your treating physician or specialist, no more than 90 days before the exam. Your AME reviews it.

      What your treating physician finds

      • The condition is stable
      • No symptoms or complications associated with diabetes
      • No side effects from the medication
      • No low blood sugar (hypoglycemic events: symptoms, or glucose 70 mg/dl or less) that required intervention in the past 12 months
    • A1C

      Within 90 days before the exam

      A current A1C, taken within the last 90 days.

      Result

      • 6.4% or lessCurrent A1C
      • Never 6.5% or greaterHistory
    • The status report form

      The FAA's Weight Loss Management or Prediabetes Status Report, filled in by the provider who prescribes your medication.

      The form asks for

      • The reason for the medication: prediabetes or hyperglycemia, or weight loss management
      • The dates of the last clinical encounter and of the most recent medication change
      • The A1C value and date, dated within 90 days of the exam
      • Any side effects from medications
      • Any low blood sugar episode (hypoglycemia) in the past year
      • Whether you take any form of insulin
      • Any clinical concerns
      • All current medications, for any condition

      Once it is filled in

      • A narrative, tests and the like attached for any YES answer
      • Returned to your AME, to upload into your FAA file
    Show the FAA's words: Progress note, A1C and status report form

    the AME must review a current, detailed Clinical Progress Note generated from a clinic visit with the treating physician or specialist no more than 90 days prior to the AME exam.

    FAA source: CACI – Prediabetes Worksheet. FAA date 26 August 2026; checked by Crosscheck 14 October 2026.

    Current A1C

    Note: A1C 6.5% or greater is diagnostic for diabetes (ADA).

    Within last 90 days;

    6.4% or LESS; and

    No history ever of A1C 6.5% or greater

    FAA source: CACI – Prediabetes Worksheet. FAA date 26 August 2026; checked by Crosscheck 14 October 2026.

    This requires a current, detailed Clinical Progress Note from the treating physician and Hemoglobin A1c lab performed no more than 90 days before the AME exam.

    FAA source: Prediabetes Disposition Table. FAA date 27 September 2023; checked by Crosscheck 14 October 2026.

    WEIGHT LOSS MANAGEMENT or PREDIABETES STATUS REPORT

    Please have the provider who prescribes your medication for weight loss or prediabetes enter the information in the space below.

    Return the completed status report to your AME to upload into your FAA file.

    Reason for taking this medication:

    Prediabetes/hyperglycemia

    Weight loss management

    Date of last clinical encounter

    Date of most recent MEDICATION change

    Hemoglobin A1C lab value and date?

    A1C required only for prediabetes (dated within 90 days of the AME exam); enter n/a if medication is for weight loss only.

    Any side effects from medications?

    ANY episode of hypoglycemia in the past year?

    Does this patient take ANY form of insulin?

    Any clinical concerns?

    List ALL current medications (for any condition).

    *If any YES answers, please attach narrative, tests, etc.

    FAA source: Weight Loss and Prediabetes Status Report. FAA date 29 April 2026; checked by Crosscheck 14 October 2026.

    Treating physician finds the condition is stable and NONE of the following are present:

    Symptoms or complications associated with diabetes;

    Side effects from the medication; and/or

    Hypoglycemic events (symptoms or glucose 70 mg/dl or less) which required intervention in the past 12 months

    FAA source: CACI – Prediabetes Worksheet. FAA date 26 August 2026; checked by Crosscheck 14 October 2026.

  3. Step 3: Your medication

    The worksheet's medication list, and its observation periods.

    Only one of the medications the worksheet lists: metformin, liraglutide, semaglutide (Wegovy, by injection or oral) or tirzepatide (Zepbound).

    Observation periods

    • One weekAfter starting the medication
    • 48 hoursWith each dose increase, medication or formulation change

    Your AME should verify the one-week observation after starting.

    Show the FAA's words: Your medication

    ONLY ONE of the medications listed is used:

    AME should verify one-week observation after starting medication. (See Pharmaceuticals, Weight Loss Medication.) 48-hour observation with each dose increase, medication or formulation change.

    Indicate which one medication is used:

    metformin OR

    liraglutide OR

    semaglutide* (Wegovy) OR

    tirzepatide (Zepbound)

    *injection or oral

    FAA source: CACI – Prediabetes Worksheet. FAA date 26 August 2026; checked by Crosscheck 14 October 2026.

  4. Step 4: The separate metabolic syndrome protocol: a first Authorization

    The treating doctor's report, on which the FAA bases its decision.

    Only under the separate protocol for medication-controlled metabolic syndrome.

    Only under the separate protocol for medication-controlled metabolic syndrome.

    A report from your treating physician, with sufficient information to rule out diabetes mellitus.

    The AMCD makes the first Authorization decision; the AME may not.

    The report

    • The medication used and its dosage
    • Whether there are side effects or clinically significant low blood sugar (hypoglycemic) episodes
    • An indication of satisfactory control of the metabolic syndrome
    • An A1C from within the past 30 days

    Associated disease

    • Any cardiovascular, neurological, renal and/or ophthalmological disease, noted

    Not in itself disqualifying, but carefully evaluated for any added risk to aviation safety.

    Show the FAA's words: The separate metabolic syndrome protocol: a first Authorization

    Medication Controlled Metabolic Syndrome (Glucose Intolerance, Impaired Glucose tolerance, Impaired Fasting Glucose, Insulin Resistance, and Pre-Diabetes)

    The initial Authorization determination will be made on the basis of a report from the treating physician. There must be sufficient information to rule out diabetes mellitus.

    The initial Authorization decision is made by the AMCD and may not be made by the Examiner.

    FAA source: Guide for Aviation Medical Examiners – Medication Controlled Metabolic Syndrome. FAA date 26 July 2023; checked by Crosscheck 14 October 2026.

    For favorable consideration, the report must contain a statement regarding the medication used, dosage, the absence or presence of side effects and clinically significant hypoglycemic episodes, and an indication of satisfactory control of the metabolic syndrome. The results of an A1C hemoglobin determination within the past 30 days must be included.

    FAA source: Guide for Aviation Medical Examiners – Medication Controlled Metabolic Syndrome. FAA date 26 July 2023; checked by Crosscheck 14 October 2026.

    Note must also be made of the presence of cardiovascular, neurological, renal, and/or ophthalmological disease. The presence of one or more of these associated diseases will not be, per se, disqualifying but the disease(s) must be carefully evaluated to determine any added risk to aviation safety.

    FAA source: Guide for Aviation Medical Examiners – Medication Controlled Metabolic Syndrome. FAA date 26 July 2023; checked by Crosscheck 14 October 2026.

What the examiner checks

It depends on which row of the FAA's table describes the case.

  • Row AExaminer issuesExaminer can issue

    The table says ISSUE where the examiner can determine the condition is under control, the current medications are acceptable and there are no symptoms that would interfere with flight duties, and has the examiner annotate this information in Block 60.

  • Row BWorksheetCACI

    The table sends the examiner to the CACI worksheet for prediabetes and the Weight Loss Management or Prediabetes Status Report, and says this requires a current, detailed progress note from the treating physician and an A1C performed no more than 90 days before the exam. If the pilot meets all the worksheet's criteria and is otherwise qualified, the table says ISSUE, and has the examiner annotate the correct CACI statement in Block 60 and keep the required supporting information on file.

  • Row CDefers to the FAASpecial Issuance

    The table has the examiner defer and submit either the Diabetes or Hyperglycemia on Medications Status Report or a current, detailed progress note from the treating physician containing all the required information listed in that status report, to the FAA for a possible Special Issuance, and annotate the elements or findings in Block 60.

    If the examiner defers
Show the FAA's words: what the examiner does on each row
  1. Row A · Examiner can issue

    Treated with lifestyle intervention. The table says ISSUE where the examiner can determine the condition is under control, the current medications are acceptable and there are no symptoms that would interfere with flight duties, and has the examiner annotate this information in Block 60.

    Treated with lifestyle intervention If the AME can determine the condition is: Under control; Current medications are acceptable; and The individual has no symptoms that would interfere with flight duties: ISSUE Annotate this information in Block 60.

    FAA source: Prediabetes Disposition Table. FAA date 27 September 2023. Checked by Crosscheck 14 October 2026

  2. Row B · CACI

    Treated with one non-insulin diabetic medication component. The table sends the examiner to the CACI worksheet for prediabetes and the Weight Loss Management or Prediabetes Status Report, and says this requires a current, detailed progress note from the treating physician and an A1C performed no more than 90 days before the exam. If the pilot meets all the worksheet's criteria and is otherwise qualified, the table says ISSUE, and has the examiner annotate the correct CACI statement in Block 60 and keep the required supporting information on file.

    Treated with ONE diabetic medication (non-insulin) component See the CACI – Prediabetes Worksheet and the Weight Loss Management or Prediabetes Status Report … This requires a current, detailed Clinical Progress Note from the treating physician and Hemoglobin A1c lab performed no more than 90 days before the AME exam. … If the pilot meets all CACI worksheet criteria and is otherwise qualified: ISSUE Annotate the correct CACI statement in Block 60 and keep the required supporting information on file.

    FAA source: Prediabetes Disposition Table. FAA date 27 September 2023. Checked by Crosscheck 14 October 2026

  3. Row C · Special Issuance

    Treated with two or more non-insulin diabetic medication components. The table has the examiner defer and submit either the Diabetes or Hyperglycemia on Medications Status Report or a current, detailed progress note from the treating physician containing all the required information listed in that status report, to the FAA for a possible Special Issuance, and annotate the elements or findings in Block 60.

    Treated with TWO (2) or more diabetic medication (non-insulin) components … Submit either: … Diabetes or Hyperglycemia on Medications Status Report … A current, detailed Clinical Progress Note from the treating physician which contains all the required information listed in the above status report. … DEFER Submit the information to the FAA for a possible Special Issuance Annotate (elements or findings) in Block 60.

    FAA source: Prediabetes Disposition Table. FAA date 27 September 2023. Checked by Crosscheck 14 October 2026

The CACI worksheet's criteria

Row B: one diabetes medicine, not insulin

Before you begin

  • Not: Anyone who has ever had an A1C of 6.5% or greater
  • Not: Diabetes in remission (diet-controlled)
  • Not: Diabetes treated with medication, including insulin
  • Not: Diabetes insipidus

Progress note

  • The condition is stable
  • No symptoms or complications associated with diabetes
  • No side effects from the medication
  • No low blood sugar (hypoglycemic events: symptoms, or glucose 70 mg/dl or less) that required intervention in the past 12 months

A1C

  • 6.4% or lessCurrent A1C
  • Never 6.5% or greaterHistory

Your medication

  • One weekAfter starting the medication
  • 48 hoursWith each dose increase, medication or formulation change

Your AME should verify the one-week observation after starting.

Show the FAA's words: the CACI worksheet's criteria for Prediabetes
  1. A current A1C

    FAA criterion: an A1C from within the last 90 days, of 6.4% or less, with no history ever of an A1C of 6.5% or greater. The worksheet notes, citing the ADA, that 6.5% or greater is diagnostic for diabetes. The table's CACI row says the A1C lab is performed no more than 90 days before the AME exam.

    Current A1C … Note: A1C 6.5% or greater is diagnostic for diabetes (ADA). … Within last 90 days; … 6.4% or LESS; and … No history ever of A1C 6.5% or greater

    FAA source: CACI – Prediabetes Worksheet. FAA date 26 August 2026. Checked by Crosscheck 14 October 2026

    This requires a current, detailed Clinical Progress Note from the treating physician and Hemoglobin A1c lab performed no more than 90 days before the AME exam.

    FAA source: Prediabetes Disposition Table. FAA date 27 September 2023. Checked by Crosscheck 14 October 2026

  2. Never an A1C of 6.5% or greater

    The worksheet says, above its criteria, that if the applicant has ever had an A1C of 6.5% or greater, do not use this CACI.

    If the applicant has EVER had an A1C OF 6.5% OR GREATER, DO NOT USE THIS CACI.

    FAA source: CACI – Prediabetes Worksheet. FAA date 26 August 2026. Checked by Crosscheck 14 October 2026

  3. The medication is used for prediabetes

    The worksheet's acceptable answer for what the medication is used for is prediabetes. Its note says diabetes in remission (diet-controlled), diabetes treated with medication (including insulin), or diabetes insipidus do not qualify for this CACI.

    AME MUST REVIEW ACCEPTABLE CERTIFICATION CRITERIA … Medication is used for: … Note: Diabetes in remission (diet-controlled), diabetes treated with medication (including insulin), or diabetes insipidus DO NOT qualify for this CACI. … [ ] Prediabetes

    FAA source: CACI – Prediabetes Worksheet. FAA date 26 August 2026. Checked by Crosscheck 14 October 2026

  4. Stable, with none of the worksheet's listed findings present

    FAA criterion: the treating physician finds the condition is stable and none of the following are present: symptoms or complications associated with diabetes; side effects from the medication; and/or hypoglycemic events (symptoms or glucose 70 mg/dl or less) which required intervention in the past 12 months.

    Treating physician finds the condition is stable and NONE of the following are present: … Symptoms or complications associated with diabetes; … Side effects from the medication; and/or … Hypoglycemic events (symptoms or glucose 70 mg/dl or less) which required intervention in the past 12 months

    FAA source: CACI – Prediabetes Worksheet. FAA date 26 August 2026. Checked by Crosscheck 14 October 2026

  5. One medication, from a list of four

    FAA criterion: only one of the medications the worksheet lists is used. The worksheet names metformin, liraglutide, semaglutide (Wegovy) and tirzepatide (Zepbound), noting that semaglutide may be by injection or oral. It says the examiner should verify a one-week observation after starting the medication, and lists a 48-hour observation with each dose increase, medication or formulation change.

    ONLY ONE of the medications listed is used: … AME should verify one-week observation after starting medication. (See Pharmaceuticals, Weight Loss Medication.) 48-hour observation with each dose increase, medication or formulation change. … Indicate which one medication is used: … metformin OR … liraglutide OR … semaglutide* (Wegovy) OR … tirzepatide (Zepbound) … *injection or oral

    FAA source: CACI – Prediabetes Worksheet. FAA date 26 August 2026. Checked by Crosscheck 14 October 2026

If the examiner defersSpecial Issuance

The table marks DEFER where the condition is treated with two or more non-insulin diabetic medication components.

What the FAA lists to send

  1. Item 1. Either the Diabetes or Hyperglycemia on Medications Status Report, where the treating physician must clearly indicate the reason for the medication and whether there is any history of diabetes.
  2. Item 2. Or a current, detailed clinical progress note from the treating physician which contains all the required information listed in that status report. It must include the indication for the medication and whether there is any history of diabetes, and, under it, the table lists an A1C performed no more than 90 days before the exam.
Show the FAA's words: if the examiner defers

When the examiner defers

  1. Reason 1

    The table marks DEFER where the condition is treated with two or more non-insulin diabetic medication components.

    Treated with TWO (2) or more diabetic medication (non-insulin) components … DEFER Submit the information to the FAA for a possible Special Issuance

    FAA source: Prediabetes Disposition Table. FAA date 27 September 2023. Checked by Crosscheck 14 October 2026

What the FAA lists to send

  1. Item 1

    Either the Diabetes or Hyperglycemia on Medications Status Report, where the treating physician must clearly indicate the reason for the medication and whether there is any history of diabetes.

    Submit either: … Diabetes or Hyperglycemia on Medications Status Report … (The treating physician must clearly indicate the reason for the medication and if there is any history of diabetes.)

    FAA source: Prediabetes Disposition Table. FAA date 27 September 2023. Checked by Crosscheck 14 October 2026

  2. Item 2

    Or a current, detailed clinical progress note from the treating physician which contains all the required information listed in that status report. It must include the indication for the medication and whether there is any history of diabetes, and, under it, the table lists an A1C performed no more than 90 days before the exam.

    A current, detailed Clinical Progress Note from the treating physician which contains all the required information listed in the above status report. … It must include the indication for the medication and if there is any history of diabetes or not; … Hemoglobin A1c lab performed no more than 90 days before the AME exam.

    FAA source: Prediabetes Disposition Table. FAA date 27 September 2023. Checked by Crosscheck 14 October 2026

What a Special Issuance is

The Guide says an Authorization for Special Issuance, valid for a specified period, may be granted at the Federal Air Surgeon's discretion to a person who does not meet the established medical standards, if the person shows to the satisfaction of the Federal Air Surgeon that the duties authorized by the class of certificate applied for can be performed without endangering public safety during the period the Authorization would be in force.

How the FAA pathways work

At later examsAASI

First and second class
Every year
Third class
At each required exam

The worksheet says first- and second-class applicants must provide this information every year, and third-class applicants must provide it with each required exam.

Show the FAA's words: how often the FAA asks again
Applicants for first- or second-class must provide this information annually; applicants for third-class must provide the information with each required exam.

FAA source: CACI – Prediabetes Worksheet. FAA date 26 August 2026. Checked by Crosscheck 14 October 2026

Under an Authorization, the AASI page lists what the pilot brings for the examiner to reissue: the Authorization itself and a current, detailed progress note from no more than 90 days before the exam, verifying no interim development of diabetes and/or no low blood sugar requiring intervention or significant side effects, together with an A1C of 6.4 or less from no more than 90 days before recertification.

Show the FAA's words: at later exams
AMEs may re-issue an airman medical certificate under the provisions of an Authorization, if the applicant provides the following: An Authorization granted by the FAA; and … A current, detailed clinical progress note performed no more than 90 days before the AME exam verifying: No interim development of diabetes; and/or … No hypoglycemia requiring intervention or significant side effects … Hemoglobin A1C is 6.4 or less (no more than 90 days before recertification)

FAA source: AASI for Prediabetes or Overweight/Obesity Treated with Medication. FAA date 27 September 2023. Checked by Crosscheck 14 October 2026

What AASI is

AASI stands for AME Assisted Special Issuance. The Guide describes it as a process that lets the examiner reissue a certificate under the provisions of an Authorization for Special Issuance, to an applicant who has a medical condition that is disqualifying under 14 CFR part 67.

How the FAA pathways work
  • Under the separate protocol: the report for a reissue under the Authorization

    Under the separate protocol for medication-controlled metabolic syndrome, a reissue of a medical certificate under the provisions of an Authorization is also made on the basis of reports from the treating physician. The report must contain the same information required for initial issuance and specifically reference the presence or absence of satisfactory control, any change in the dosage or type of medication, and the presence or absence of complications or side effects from the medication.

    Show the FAA's words: Under the separate protocol: the report for a reissue under the Authorization
    Re-issuance of a medical certificate under the provisions of an Authorization will also be made on the basis of reports from the treating physician. The contents of the report must contain the same information required for initial issuance and specifically reference the presence or absence of satisfactory control, any change in the dosage or type of medication, and the presence or absence of complications or side effects from the medication.

    FAA source: Guide for Aviation Medical Examiners – Medication Controlled Metabolic Syndrome. FAA date 26 July 2023. Checked by Crosscheck 14 October 2026

  • Under the separate protocol: the treating physician's follow-up, at least annually

    Under the separate protocol for medication-controlled metabolic syndrome, at a minimum, follow-up evaluation by the treating physician of the applicant's metabolic syndrome status is required annually, for all classes of medical certificate.

    Show the FAA's words: Under the separate protocol: the treating physician's follow-up, at least annually
    At a minimum, followup evaluation by the treating physician of the applicant's metabolic syndrome status is required annually for all classes of medical certificates.

    FAA source: Guide for Aviation Medical Examiners – Medication Controlled Metabolic Syndrome. FAA date 26 July 2023. Checked by Crosscheck 14 October 2026

  • The Authorization granted by the FAA

    The AASI page's list for a reissue includes the Authorization the FAA granted.

    Show the FAA's words: The Authorization granted by the FAA
    AMEs may re-issue an airman medical certificate under the provisions of an Authorization, if the applicant provides the following: … An Authorization granted by the FAA; and

    FAA source: AASI for Prediabetes or Overweight/Obesity Treated with Medication. FAA date 27 September 2023. Checked by Crosscheck 14 October 2026

  • A current, detailed progress note

    For a reissue the AASI page asks for a current, detailed progress note from no more than 90 days before the exam, verifying no interim development of diabetes and/or no low blood sugar requiring intervention or significant side effects.

    Show the FAA's words: A current, detailed progress note
    AMEs may re-issue an airman medical certificate under the provisions of an Authorization, if the applicant provides the following: … A current, detailed clinical progress note performed no more than 90 days before the AME exam verifying: … No interim development of diabetes; and/or … No hypoglycemia requiring intervention or significant side effects

    FAA source: AASI for Prediabetes or Overweight/Obesity Treated with Medication. FAA date 27 September 2023. Checked by Crosscheck 14 October 2026

  • An A1C of 6.4 or less

    The AASI page asks for an A1C of 6.4 or less from no more than 90 days before recertification.

    Show the FAA's words: An A1C of 6.4 or less
    Hemoglobin A1C is 6.4 or less (no more than 90 days before recertification)

    FAA source: AASI for Prediabetes or Overweight/Obesity Treated with Medication. FAA date 27 September 2023. Checked by Crosscheck 14 October 2026

  • What the Authorization letter comes with

    The AASI page says the Authorization letter comes with attachments that specify the information the treating doctors must provide for the reissue determination.

    Show the FAA's words: What the Authorization letter comes with
    The Authorization letter is accompanied by attachments that specify the information that treating physician(s) must provide for the re-issuance determination.

    FAA source: AASI for Prediabetes or Overweight/Obesity Treated with Medication. FAA date 27 September 2023. Checked by Crosscheck 14 October 2026

  • When the examiner defers a reissue

    The AASI page says the examiner must defer to the AMCD or Region if additional diabetes medications are added, if diabetes develops, and/or for any other reason for not renewing an AASI.

    Show the FAA's words: When the examiner defers a reissue
    The AME must defer to the AMCD or Region if: Additional diabetes medications are added; Development of diabetes; and/or Any other reason for not renewing an AASI

    FAA source: AASI for Prediabetes or Overweight/Obesity Treated with Medication. FAA date 27 September 2023. Checked by Crosscheck 14 October 2026

Good to know

Points from the FAA's own documents that are easy to miss.

  • CACI expanded to weight-loss use

    The worksheet notes that the CACI was expanded to include diabetic medication taken for weight loss.

    Show the FAA's words: good to know, 1
    NOTE: CACI expanded to include diabetic medication taken for weight loss.

    FAA source: CACI – Prediabetes Worksheet. FAA date 26 August 2026. Checked by Crosscheck 14 October 2026

  • The form's only GLP-1 instruction

    Where the pilot takes a GLP-1, the form tells the prescriber to verify there are no psychiatric side effects. The FAA's weight-loss medication page lists liraglutide, semaglutide (Wegovy) and tirzepatide (Zepbound) under GLP-1 agonist, and the prediabetes worksheet names all three.

    Show the FAA's words: good to know, 2
    Please have the provider who prescribes your medication for weight loss or prediabetes enter the information in the space below. … (If taking GLP-1, verify no psychiatric side effects.)

    FAA source: Weight Loss and Prediabetes Status Report. FAA date 29 April 2026. Checked by Crosscheck 14 October 2026

    GLP-1 agonist … liraglutide … semaglutide (Wegovy) [injection or oral] … tirzepatide (Zepbound) [GIP + GLP-1 Agonist]

    FAA source: Weight Loss Medications. FAA date 26 August 2026. Checked by Crosscheck 14 October 2026

    liraglutide OR … semaglutide* (Wegovy) OR … tirzepatide (Zepbound)

    FAA source: CACI – Prediabetes Worksheet. FAA date 26 August 2026. Checked by Crosscheck 14 October 2026

  • Where the form sends diabetic pilots

    The form's closing note sends a pilot diagnosed with diabetes to the FAA's diabetes address, and a pilot taking insulin to the FAA's ITDM address.

    Show the FAA's words: good to know, 3
    Note: If diagnosed with diabetes, see www.faa.gov/go/diabetic. … If taking insulin, see www.faa.gov/go/ITDM.

    FAA source: Weight Loss and Prediabetes Status Report. FAA date 29 April 2026. Checked by Crosscheck 14 October 2026

  • A separate metabolic syndrome protocol

    The FAA's protocol for medication-controlled metabolic syndrome names pre-diabetes in its title. Under it, the AMCD makes the initial Authorization decision, not the examiner, and an examiner may reissue a later certificate under the Authorization.

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    Medication Controlled Metabolic Syndrome (Glucose Intolerance, Impaired Glucose tolerance, Impaired Fasting Glucose, Insulin Resistance, and Pre-Diabetes) … The initial Authorization decision is made by the AMCD and may not be made by the Examiner. An Examiner may re-issue a subsequent airman medical certificate under the provisions of the Authorization.

    FAA source: Guide for Aviation Medical Examiners – Medication Controlled Metabolic Syndrome. FAA date 26 July 2023. Checked by Crosscheck 14 October 2026

  • Diabetes on a non-insulin medication

    The protocol says an applicant with diabetes mellitus treated with a medication other than insulin may be considered by the FAA for an Authorization. It points to the Acceptable Combinations of Diabetes Medications chart for the medications currently allowed and the required observation times.

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    An applicant with a diagnosis of diabetes mellitus treated with a medication not including insulin may be considered by the FAA for an Authorization of a Special Issuance of a Medical Certificate (Authorization). For medications currently allowed and required observation times, see chart of Acceptable Combinations of Diabetes Medications ( PDF ) .

    FAA source: Guide for Aviation Medical Examiners – Medication Controlled Metabolic Syndrome. FAA date 26 July 2023. Checked by Crosscheck 14 October 2026

  • Counselling, warnings and medication changes

    The protocol says an applicant with metabolic syndrome should be counseled by the examiner on the significance of the disease and its possible complications, including the possibility of developing diabetes mellitus. It says the applicant should be told of possible hypoglycemic reactions and cautioned to stay under close medical surveillance by the treating physician. After a medication or dose change, the applicant should not perform airman duties until they and the treating physician conclude the condition is under control, stable and presents no risk to aviation safety; the list ends with consulting the issuing examiner, the AMCD or the RFS.

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    An applicant with metabolic syndrome should be counseled by his or her Examiner regarding the significance of the disease and its possible complications, including the possibility of developing diabetes mellitus. … The applicant should be informed of the potential for hypoglycemic reactions and cautioned to remain under close medical surveillance by his or her treating physician. … The applicant should also be advised that should their medication be changed or the dosage modified, the applicant should not perform airman duties until the applicant and treating physician has concluded that the condition is: … under control; … stable; … presents no risk to aviation safety; and … consults with the Examiner who issued the certificate, AMCD or RFS .

    FAA source: Guide for Aviation Medical Examiners – Medication Controlled Metabolic Syndrome. FAA date 26 July 2023. Checked by Crosscheck 14 October 2026

  • When the examiner must defer

    Under the protocol, an adverse change -- diabetes mellitus developing, poor control, or complications or side effects from the medication -- or an associated systemic disease appearing means the examiner must defer the case, with all documentation, to the AMCD.

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    In the event of an adverse change in the applicant's status (development of diabetes mellitus, poor control or complications or side effects from the medication), or the appearance of an associated systemic disease, an Examiner must defer the case with all documentation to the AMCD for consideration.

    FAA source: Guide for Aviation Medical Examiners – Medication Controlled Metabolic Syndrome. FAA date 26 July 2023. Checked by Crosscheck 14 October 2026

  • After a deferred case is reviewed

    If the AMCD reviews the deferred case and decides reissuance is appropriate, the examiner may again be given authority to reissue under the Authorization, based on the treating physician's data, including what may be required to assess associated medical conditions.

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    If, upon further review of the deferred case, AMCD decides that re-issuance is appropriate, the Examiner may again be given the authority to re-issue the medical certificate under the provisions of the Authorization based on data provided by the treating physician, including such information as may be required to assess the status of associated medical condition(s).

    FAA source: Guide for Aviation Medical Examiners – Medication Controlled Metabolic Syndrome. FAA date 26 July 2023. Checked by Crosscheck 14 October 2026

  • What a progress note must include

    In most cases it should come from a visit with the treating physician no more than 90 days ago, and cover the history, medications with dosages and side effects, exam findings, test results, diagnosis, assessment and plan, prognosis and follow-up. The FAA's sheet says to make sure the physician adds the prognosis. A portal note or an After Visit Summary that does not meet these criteria is not enough, and neither is a simple "ok to fly" letter. The FAA's documents also call it a status report.

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    your patient portal to print out “notes” or an “After Visit Summary (AVS).” … Patient Portal notes or an AVS that do not meet the criteria listed below for a detailed Clinical Progress Note are NOT sufficient for FAA purposes. … To be “current,” in MOST CASES, the detailed Clinical Progress Note should be from an evaluation in which you saw your treating physician no more than 90 days ago. … It Must include the following items: … A summary of the history of the condition, … Current medications, dosages, and side effects (if any); … Clinical exam findings; … Results of any testing performed; … Diagnosis; … Assessment and Plan; … Prognosis (This item may not be on a standard progress note, make sure your physician adds this information.); and … Follow-up … Please note: A letter stating, “Mr. Smith is ok to fly” (or any other simple note), is NOT a current, detailed Clinical Progress Note and is NOT acceptable. … You may also see this called a “current status report” or “status report” in current FAA Guidance. Any reference to a “status report” equals the criteria listed on this sheet.

    FAA source: Pilot Information – What a Detailed Clinical Progress Note must contain. FAA date 25 September 2024. Checked by Crosscheck 14 October 2026

  • Only one non-insulin medication

    The table sends one non-insulin diabetic medication component to the worksheet. The worksheet's criterion is that only one of the medications it lists is used: metformin, liraglutide, semaglutide or tirzepatide.

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    Treated with ONE diabetic medication (non-insulin) component See the CACI – Prediabetes Worksheet

    FAA source: Prediabetes Disposition Table. FAA date 27 September 2023. Checked by Crosscheck 14 October 2026

    ONLY ONE of the medications listed is used: … metformin OR … liraglutide OR … semaglutide* (Wegovy) OR … tirzepatide (Zepbound)

    FAA source: CACI – Prediabetes Worksheet. FAA date 26 August 2026. Checked by Crosscheck 14 October 2026

  • A first AASI application is deferred

    The AASI says that if this is a first-time application for this AASI and the applicant has all the medical information needed for a determination, the examiner must defer and submit it all to the AMCD or RFS for the initial determination.

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    If this is a first-time application for an AASI for the above disease/condition, and the applicant has all the requisite medical information necessary for a determination, the AME must defer and submit all of the documentation to the AMCD or RFS for the initial determination.

    FAA source: AASI for Prediabetes or Overweight/Obesity Treated with Medication. FAA date 27 September 2023. Checked by Crosscheck 14 October 2026

  • Where the AASI sends diabetic pilots

    The AASI page sends a pilot diagnosed with diabetes and taking medication other than insulin to one address it prints, and a pilot taking insulin to another.

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    If diagnosed with diabetes and taking medication other than insulin see: www.faa.gov/go/diabetic … If diagnosed with diabetes and taking insulin see: www.faa.gov/go/itdm

    FAA source: AASI for Prediabetes or Overweight/Obesity Treated with Medication. FAA date 27 September 2023. Checked by Crosscheck 14 October 2026

FAA sources

Every FAA document this page relies on, with the FAA's own date and the date Crosscheck last read it. The documents to print open at the FAA, so they are always the FAA's current ones.

Each has its own page, with what the FAA's documents say about it.

Medication guidance

Medications Crosscheck lists as taken for prediabetes, each with its own page on what published FAA guidance says about it.

This reports what the FAA has published. It is not medical advice, and it does not say how the FAA or an examiner will decide a case.