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Pain

Muscle relaxants

Muscle relaxant
Other names: cyclobenzaprine, Flexeril, carisoprodol, Soma, methocarbamol, Robaxin

FAA guidance

Do not fly while taking it.

If used routinely

The examiner should defer

FAA label

DO NOT FLY

Source: FAA, DO NOT ISSUE – DO NOT FLY Medications and general No Fly wait times. FAA date 30 September 2026. Checked by Crosscheck 14 October 2026

Muscle relaxants are on the FAA's Do Not Fly list; if the pilot uses one routinely, the FAA's table says the examiner should defer.

Track your medications
More detail: Muscle relaxantsThe rest of Crosscheck's reading, in plain wordsOpen

The FAA's general no-fly wait times say pilots should not fly after the last dose of any medication until 5 times its maximum pharmacologic half-life has passed (preferred), or 5 times the maximum dose interval if the half-life is not available.

Show the FAA's words: Muscle relaxantsThe official FAA wording: three passages, each with its document and dateOpen
FAA, DO NOT ISSUE – DO NOT FLY Medications and general No Fly wait times · FAA date 30 September 2026
DO NOT FLY (DNF) MEDICATIONS
The following medications have aeromedically concerning safety profiles. All medications listed below may cause sedation or drowsiness, impairing cognitive function and seriously degrading pilot performance.
MUSCLE RELAXANTS
Including but not limited to:
carisoprodol (Soma)
cyclobenzaprine (Flexeril)
FAA, DO NOT ISSUE – DO NOT FLY Medications and general No Fly wait times · FAA date 30 September 2026
DO NOT FLY (DNF) MEDICATIONS
AMEs should caution pilots on use and provide additional No Fly wait times where applicable. If applicant is using the following medications routinely, AMEs should DEFER.
FAA, DO NOT ISSUE – DO NOT FLY Medications and general No Fly wait times · FAA date 30 September 2026
GENERAL NO FLY WAIT TIMES
For Aviation safety, pilots should not fly following the last dose of any medications until a period of time has elapsed equal to:
A. 5-times the maximum pharmacologic half-life of the medication (preferred); or
B. 5-times the maximum hour dose interval if pharmacologic half-life information is not available.
Sources and dates: Muscle relaxantsOne FAA document, with the FAA's date and when Crosscheck checked itOpen

See also

Medication guidance alone does not determine whether a pilot is medically qualified to fly. The underlying condition, dosage, side effects, medication combinations, and certification history may affect FAA eligibility.

For informational purposes only. Not legal or medical advice.