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Pain medications

What published FAA guidance says about 36 medications Crosscheck files under pain medications: each one's answer and, where there is one, its wait. Open a medication for the FAA's own words, the source and its date.

  • Acetaminophen

    Acceptable with conditions · Wait: 24 hours after the first dose (the FAA's MedGuide)Also called Tylenol, Panadol
  • Acetaminophen + aspirin + caffeine

    Acceptable with conditions · Wait: 24 hours after the first doseAlso called Excedrin
  • Aspirin

    Acceptable with conditions · Wait: 24 hours after the first dose (the FAA's MedGuide)Also called Bayer, Ascriptin, Ecotrin
  • Benzocaine

    Acceptable in the FAA document citedAlso called Anbesol, Cepacol
  • Celecoxib

    Acceptable with conditions · Wait: 24 hours after the first doseAlso called Celebrex
  • Chondroitin + glucosamine sulfate

    Acceptable in the FAA document citedAlso called Osteo Bi-Flex
  • Colchicine + probenecid

    Acceptable with conditions · Wait: 24 hours after the first doseAlso called Colbenemid, Col-Probenecid
  • Diclofenac + misoprostol

    Acceptable with conditions · Wait: 24 hours after the first doseAlso called Arthrotec
  • Diflunisal

    Acceptable with conditions · Wait: 24 hours after the first doseAlso called Dolobid
  • Etodolac

    Acceptable with conditions · Wait: 24 hours after the first doseAlso called Lodine, Todolac
  • Fenoprofen

    Acceptable with conditions · Wait: 24 hours after the first doseAlso called Nalfon
  • Flavocoxid

    Acceptable in the FAA document citedAlso called Limbrel
  • Flurbiprofen (oral)

    Acceptable with conditions · Wait: 24 hours after the first doseAlso called Lurbiro, Ansaid
  • Glucosamine sulfate

    Acceptable in the FAA document citedAlso called OptiFlex-G
  • Hexylresorcinol

    Acceptable in the FAA document cited
  • Ibuprofen

    Acceptable with conditions · Wait: 24 hours after the first dose (the FAA's MedGuide)Also called Advil, Motrin
  • Indomethacin

    Acceptable with conditions · Wait: 24 hours after the first doseAlso called Indocin
  • Ketoprofen

    Acceptable with conditions · Wait: 24 hours after the first doseAlso called Orudis, Oruvail
  • Lidocaine patch and topical pain rubs

    Acceptable with conditions · Wait: 24 hours after the first dose of capsaicin (Qutenza) and none for lidocaine on the skin (the FAA's MedGuide)Also called lidocaine patch, Lidoderm, Salonpas, capsaicin
  • Meclofenamate

    Acceptable with conditions · Wait: 24 hours after the first doseAlso called Meclomen
  • Mefenamic acid

    Acceptable with conditions · Wait: 24 hours after the first doseAlso called Ponstel
  • Meloxicam

    Acceptable with conditions · Wait: 24 hours after the first doseAlso called Mobic
  • Muscle relaxants

    Do not fly while taking itAlso called cyclobenzaprine, Flexeril, carisoprodol, Soma
  • Nabumetone

    Acceptable with conditions · Wait: 24 hours after the first doseAlso called Relafen
  • Naproxen

    Acceptable with conditions · Wait: 24 hours after the first dose (the FAA's MedGuide)Also called Aleve, Naprosyn, Anaprox, Naprelan
  • Naproxen + esomeprazole

    Acceptable with conditions · Wait: 24 hours after the first doseAlso called Vimovo
  • Opioid pain relievers

    Do not fly while taking itAlso called oxycodone, OxyContin, Percocet, Percodan
  • Oxaprozin

    Acceptable with conditions · Wait: 24 hours after the first doseAlso called Daypro
  • Piroxicam

    Acceptable with conditions · Wait: 24 hours after the first doseAlso called Feldene
  • PM pain products

    Do not fly while taking it · Wait: 60 hours after diphenhydramine (the FAA's Do Not Fly table)Also called Advil PM, Tylenol PM, Aleve PM
  • Probenecid

    Acceptable with conditions · Wait: 24 hours after the first doseAlso called Probalan, Benemid
  • Salicylsalicylic acid

    Acceptable with conditions · Wait: 24 hours after the first doseAlso called Salsalate
  • SAMe

    Acceptable with conditions · Wait: 48 hours after the first doseAlso called Heptral, s-adenosylmethionine, ademetionine
  • Sedation for a procedure

    Do not fly while taking itAlso called midazolam, Versed, propofol, fentanyl
  • Sulindac

    Acceptable with conditions · Wait: 24 hours after the first doseAlso called Clinoril
  • Tolmetin

    Acceptable with conditions · Wait: 24 hours after the first doseAlso called Tolectin

Other groups of medications

Every medication Crosscheck has an FAA answer for, by group or from A to Z, with the answer and the wait on each line. New from the FAA in October 2026: the FAA's MedGuide, explained.

Medication guidance alone does not determine whether a pilot is medically qualified to fly. The underlying condition, dosage, side effects, medication combinations, and certification history may affect FAA eligibility.

For informational purposes only. Not legal or medical advice.