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Migraine

Other medications unacceptable for migraine prevention

Migraine prevention medication the FAA prohibits

FAA guidance

Do not issue.

Examiner

Do not issue: the examiner cannot issue a certificate

FAA label

UNACCEPTABLE

Source: FAA, Migraine Medication. FAA date 26 August 2026. Checked by Crosscheck 14 October 2026

The FAA documents quoted here name the class, not this medication. Crosscheck matched it through its class: Migraine prevention medication the FAA prohibits.

The FAA lists all tricyclic antidepressants, gabapentin, lacosamide, lamotrigine, lasmiditan, pregabalin, topiramate and valproic acid as unacceptable for migraine prevention, their use prohibited as a single agent or in any combination product.

Track your medications
More detail: Other medications unacceptable for migraine preventionThe rest of Crosscheck's reading, in plain wordsOpen

Each of these medicines also has its own entry.

FAA rule for migraine medication: The FAA says migraine relief or rescue medication is acceptable when used occasionally and unacceptable for daily use, and that its post-dose observation time (no-fly warning) is based on the drug's half-life. It says that if several relief medications are needed on a recurring basis to stop symptoms, this is considered a complicated migraine, and the examiner should defer. For relief or rescue medication the worksheet lists, the FAA's CACI – Migraine and Chronic Headache Worksheet says the examiner can issue if the pilot meets all of its acceptable certification criteria, which include no more than one episode per month, no more than 2 outpatient clinic or urgent care visits for symptom exacerbation in the last 12 months (even if symptoms fully resolved), and no history of in-patient hospitalizations for headaches; it says narcotics, Fiorinal, Fioricet and Midrin are not acceptable for relief or rescue. FAA, Migraine Medication

Show the FAA's words: Other medications unacceptable for migraine preventionThe official FAA wording: one passage, each with its document and dateOpen
FAA, Migraine Medication · FAA date 26 August 2026
UNACCEPTABLE – Migraine Prevention (Prophylaxis). Use prohibited as a single agent or in any combination product. ALL tricyclic antidepressants (TCA), gabapentin (Neurontin), lacosamide (Vimpat), lamotrigine (Lamictal), lasmiditan (Reyvow) [unacceptable for prophylaxis/prevention], pregabalin (Lyrica), topiramate (Topamax), valproic acid (Depakote)
Sources and dates: Other medications unacceptable for migraine preventionOne FAA document, with the FAA's date and when Crosscheck checked itOpen

See also

Medication guidance alone does not determine whether a pilot is medically qualified to fly. The underlying condition, dosage, side effects, medication combinations, and certification history may affect FAA eligibility.

For informational purposes only. Not legal or medical advice.