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Migraine medications

What published FAA guidance says about 22 medications Crosscheck files under migraine medications: each one's answer and, where there is one, its wait. Open a medication for the FAA's own words, the source and its date.

  • Almotriptan

    Acceptable with conditions · Wait: 24 hours after each doseAlso called Axert
  • Botox for migraine prevention

    Special issuance required · Wait: 1 month ground trial when startingAlso called Botox, botulinum toxin, botulinum toxin type A, onabotulinumtoxinA
  • CGRP injections and Qulipta for migraine prevention

    Acceptable with conditions · Wait: 7 days ground trial when startingAlso called atogepant, Qulipta, erenumab, Aimovig
  • Eletriptan

    Acceptable with conditions · Wait: 48 hours after each dose in the FAA's migraine medication sheet and the FAA's CACI – Migraine and Chronic Headache WorksheetAlso called Relpax
  • Ergot derivatives for migraine

    Acceptable with conditions · Wait: 48 hours after each dose of dihydroergotamineAlso called dihydroergotamine, Migranal, DHE, ergotamine + caffeine
  • Fioricet and Fiorinal (butalbital)

    Do not issueAlso called Fioricet, Fiorinal, butalbital, Esgic
  • Frovatriptan

    Acceptable with conditions · Wait: 48 hours after each dose in the FAA's migraine medication sheet and the FAA's CACI – Migraine and Chronic Headache WorksheetAlso called Frova
  • Gepants for stopping a migraine

    Acceptable with conditions · Wait: 24 hours after each dose in the FAA's migraine medication sheet and the FAA's CACI – Migraine and Chronic Headache WorksheetAlso called rimegepant, Nurtec, Nurtec ODT, ubrogepant
  • Ketorolac for severe headache

    Special issuance required · Wait: 36 hours after each doseAlso called ketorolac, Toradol, Sprix
  • Lasmiditan

    Differs by what it is taken forAlso called Reyvow
  • Meloxicam + rizatriptan

    Acceptable with conditions · Wait: 24 hours after each doseAlso called Symbravo
  • Midrin

    Do not issueAlso called isometheptene, dichloralphenazone, Prodrin
  • Naratriptan

    Acceptable with conditions · Wait: 24 hours after each doseAlso called Amerge
  • Nausea medication used with a migraine

    Acceptable with conditions · Wait: 36 hours after each dose of metoclopramideAlso called ondansetron, Zofran, metoclopramide, Reglan
  • Opioids for migraine

    Do not issueAlso called codeine for migraine, hydrocodone for migraine, oxycodone for migraine
  • Rizatriptan

    Acceptable with conditions · Wait: 24 hours after each doseAlso called Maxalt, Maxalt-MLT
  • Sumatriptan

    Acceptable with conditions · Wait: 24 hours after each doseAlso called Imitrex, Imitrex STATdose, Onzetra, Zembrace
  • Sumatriptan + naproxen

    Acceptable with conditions · Wait: 24 hours after each doseAlso called Treximet
  • Topiramate for migraine prevention

    Do not issueAlso called topiramate, Topamax, Trokendi XR, Qudexy XR
  • Valproic acid for migraine prevention

    Do not issueAlso called valproic acid, Depakote, Depakene, divalproex
  • Zolmitriptan

    Acceptable with conditions · Wait: 24 hours after each doseAlso called Zomig, Zomig-ZMT

Other groups of medications

Every medication Crosscheck has an FAA answer for, by group or from A to Z, with the answer and the wait on each line. New from the FAA in October 2026: the FAA's MedGuide, explained.

Medication guidance alone does not determine whether a pilot is medically qualified to fly. The underlying condition, dosage, side effects, medication combinations, and certification history may affect FAA eligibility.

For informational purposes only. Not legal or medical advice.